All codes/U0221

U0221

Lost Communication with Door Control Module E

Moderate severity

The body bus has lost door control module E (e.g. second sliding door). Functions on this door stop working.

The body bus has lost door control module E (e.g. second sliding door). Functions on this door stop working.

Common causes

  • Door harness damaged

    One of the most commonly reported causes for this code — check this first.

    high

    Typical part cost: $90-770

  • Gateway module routing CAN messages incorrectly

    Less common, but worth ruling out after the more likely causes.

    low

    Typical part cost: $90-770

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First things to check

  1. 1Confirm the code with a scan tool and check for additional related codes.
  2. 2Inspect the relevant sensors, wiring, and connectors for damage or corrosion.

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Related codes

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Frequently asked questions

What does U0221 mean?

U0221 means "Lost Communication with Door Control Module E". It is a generic OBD-II code that points to a fault in the network / communication.

What are the most common causes of U0221?

door harness damaged; gateway module routing can messages incorrectly; can terminating resistor (120 ω) drifted out of spec — these are the most commonly reported causes. Verify with a proper diagnosis before replacing parts, or use the Wrenchify app for a vehicle-specific diagnosis.

Can I keep driving with this code?

The vehicle is usually drivable for short distances, but the problem can worsen or affect emissions. Diagnose and repair as soon as practical. Use the Wrenchify app for a full diagnosis specific to your vehicle.

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